Academic Year/course:
2023/24
543 - Master's in Molecular Chemistry and Homogeneous Catalysis
60459 - Asymmetric catalysis
Syllabus Information
Academic year:
2023/24
Subject:
60459 - Asymmetric catalysis
Faculty / School:
100 - Facultad de Ciencias
Degree:
543 - Master's in Molecular Chemistry and Homogeneous Catalysis
ECTS:
2.0
Year:
1
Semester:
Second semester
Subject type:
Optional
Module:
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1. General information
The field of study of the subject is the application of chiral compounds as catalysts in asymmetric synthesis. It addresses the design of ligands and transition metal chiral compounds for application in asymmetric catalysis. This subject also covers in depth the reaction mechanism of the main enantioselective catalytic systems as well as their practical applications.
The overall objective of the subject is to study the general principles of asymmetric catalysis and the main catalytic systems based on chiral transition metal compounds, emphasizing the study of the reaction mechanisms.
These approaches and objectives are aligned with some of the Sustainable Development Goals, SDGs, of the 2030 Agenda (https://www.un.org/sustainabledevelopment/es/) and certain specific targets, so that the acquisition of the learning results of the subject provides training and competence to the student to contribute to some extent to the achievement of goals 2, 7, 9, 12 and 13.
2. Learning results
To know the general principles of stereochemistry and stereodifferentiation in catalysis.
To know the most important enantioselective catalytic processes from the industrial and technological point of view. To analyze the most relevant parameters that characterize the efficiency of a catalyst in asymmetric reactions. To assess the asymmetric catalysis potential of homogeneous catalysts depending on their nature.
To understand and interpret new knowledge in asymmetric catalysis.
3. Syllabus
Topic 1. Introduction to asymmetric catalysis
Topic 2. Asymmetric hydrogenation
Topic 3. Asymmetric hydrogen transfer
Topic 4. Asymmetric Diels-Alder
Topic 5. Friedel-Crafts asymmetric
Topic 6. Asymmetric allylic alkyl alkylation
Topic 7. Asymmetric oxidation
4. Academic activities
Expository-participative classes: 14h
Problem solving and seminars: 2h
Directed work presented in the classroom: 4h
Personal work and tutorials in small groups or individual: 28h
Assessment test: 2h
The learning process designed for the subject is essentially based on lectures of a participative nature that will be complemented with seminars and tutorials. In order to foster critical thinking and communication skills, the oral presentation of relevant results from the scientific literature and their discussion in groups has been proposed.
5. Assessment system
The continuous assessment of this subject is based on the following activities with the weighting shown below:
Participation in class, solving of exercises and questions proposed by the teacher, as well as a test on the content of the solved questions (40 %). Oral presentation of the contents of selected scientific articles and participation in group discussion (60 %).
Students who do not opt for continuous assessment or who do not pass the subject by this procedure may take a global test, which will account for 100% of the final grade, both in the first and in the second call. The global test will consist of a written test based on theoretical and practical questions on the contents covered in the subject. Students who wish to improve their continuous assessment grade may also take the global test in the first call, keeping the best of the grades obtained.